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Writer's pictureGuru Darshan M J

Lil' Vision


"Forget about all the reasons why something may not work; you only need to find one good reason why it will," said Dr. Robert Anthony. This powerful quote resonates with all aspects of our lives, whether they pertain to work, goals, or our personal lives.


Unfortunately, life isn't always fair to everyone, and it can be particularly harsh on couples who cannot conceive. Being labeled as infertile or enduring societal jeers due to this circumstance adds an immense emotional burden on them. The pain associated with such challenges might eventually lead them to abandon their dream of starting a family.


But the birth of Louise Brown on July 25th, 1978, due to a technique called IVF (In Vitro Fertilization), envisioned by Dr. Robert Edwards, a British reproductive biologist, his colleague Dr. Patrick Steptoe, a gynecologist, and their team brought immeasurable joy to her parents but also instilled a beacon of hope in millions of couples unable to conceive worldwide.


In vitro fertilization (IVF) is a medical procedure that has revolutionized the way we think about fertility, sometimes breaking barriers instilled by nature. It involves the fertilization of an egg outside of the body, in a laboratory using a test tube or a petri dish before being implanted into the uterus. Since the first successful IVF birth in 1978, the technology has come a long way, recently allowing same-sex couples and families of three individuals to have a child, bringing a revolution to the concept of the word "family."


Even though IVF has provided a beacon of hope for couples who have been struggling to conceive, the procedure was controversial, and many people were skeptical about its success. It took several years for this beacon to glow brightly and become widely accepted as a successful treatment for infertility today.


Today, IVF clinics offer a variety of treatments, including intracytoplasmic sperm injection (ICSI), preimplantation genetic testing (PGT), frozen embryo transfer (FET), Fallopian Tube Embryo Transfer (FTET), and Oocyte cryopreservation (Egg Freezing). These advancements have increased the success rates of IVF and reduced the risks associated with the procedure using artificial intelligence (AI) and machine learning. Using AI can help predict the likelihood of success for individual patients based on factors such as age, hormone levels, and previous IVF cycles, providing tailored treatments to couples, and increasing their chances of success.


The future of IVF is bright as advancements in technology lead to optimized procedures with high chances of success. Additionally, it may even become more accessible and affordable for couples who are struggling with infertility in all strata of society.


One area of promising research is the use of stem cells to create eggs and sperm. This could potentially eliminate the need for donor eggs and sperm, especially for single parents wanting to conceive a child, and it could even allow same-sex couples to have their biological children without the need for a surrogate mother.


There is also the concept of three parents conceiving a child, typically referring to a technique called mitochondrial donation or mitochondrial replacement therapy (MRT). MRT involves combining genetic material from two parents with the mitochondrial DNA (mtDNA) of a third parent; this process was initially used to prevent the transmission of mitochondrial diseases to offspring.


However, IVF is not without its emotional and social struggles. The process itself can be stressful, and the success rates are often not 100%. The cost of the treatment can also be a major barrier for many couples. Additionally, IVF raises ethical questions about the use and misuse of embryos and the creation of "designer babies" using gene editing tools.


Overall, IVF is a technology that can bring joy, laughter, love, and endless possibilities to a family. However, it is essential to realize that if misused, it has the potential to create a dystopian world.



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